Toxicity generating mechanisms

This post assumes you are well-versed with electrophiles and nucleophiles along with basics of Biology. If not, here are some links for you that can help. Video – DNA (Khan Academy) Nucleophiles, Electrophiles and Leaving Groups Electrophilic substitution or those metabolized to electrophilic species are capable of reacting covalently with nucleophilic substituents of cellular macromoleculesContinue reading “Toxicity generating mechanisms”