It is a such a mess without proper organization and good design of experiments. Without proper organization and good design of experiments you lose time, energy, resources and peace of mind. Design of experiments should be a requisite for greener research.
Many of the current statistical approaches to designed experiments originate from the work of R. A. Fisher in the early part of the 20th century. Fisher demonstrated how taking the time to seriously consider the design and execution of an experiment before trying it helped avoid frequently encountered problems in analysis. Key concepts in creating a designed experiment include blocking, randomization and replication.
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